ABSTRACT
The activity of azithromycin against enteritis-producing agents other than Campylobacter spp. was studied. The susceptibility to azithromycin, through gradient test, of 88 clinical isolates (51 Salmonella spp., 23 Aeromonas spp., 10 Shigella sonnei and 4 Yersinia enterocolitica) for one year was studied prospectively. The results were compared with the activity of ampicillin, trimethoprim-sulfamethoxazole and ciprofloxacin by microdilution. For azithromycin, the minimum inhibitory concentration (MIC) 50 and MIC90 were 4 and 12 mg/l, respectively. Six (6.8%) isolates were simultaneously resistant to ampicillin, trimethoprim- sulfamethoxazole and ciprofloxacin, and 3 (50%) of them presented a MIC >256 mg/l. Azithromycin may be a good empirical therapeutic option for the treatment of bacterial enteritis.
Subject(s)
Aeromonas/drug effects , Anti-Bacterial Agents/pharmacology , Azithromycin/pharmacology , Enterobacteriaceae/drug effects , Campylobacter , Gastroenteritis/microbiology , Humans , Microbial Sensitivity TestsABSTRACT
No disponible
Subject(s)
Humans , Child, Preschool , Child , Adolescent , Antigens, Bacterial/isolation & purification , Bacteriological Techniques/methods , Pharyngitis/microbiology , Streptococcus pyogenes/immunology , Sensitivity and Specificity , Streptococcus pyogenes/isolation & purification , Tonsillitis/microbiologyABSTRACT
No disponible
